Specific features of deep structure and tectonics of the Magadan and West Kamchatka shelves in the Sea of Okhotsk and adjacent area of the Kamchatka Peninsula were verified by geological and geophysical modelling. The investigations aimed at studying the localization pattern of hydrocarbon fields on the northern flank of the Okhotsk oil and gas province are based on results of regional and medium-scale geological surveys and prognostic and prospecting studies, geophysical survey data (gravity anomaly field Δg in the Bouguer reduction with an intermediate layer density 2.67 g/cm3, anomalous magnetic field ΔTа, regional seismic lines and the results of their generalizations), and petrophysical well survey materials. Different algorithms for solving the direct and inverse problems as well as pattern recognition with and without training were used in processing and interpretation of potential geophysical fields. The studies showed that the specific features of deep structure and tectonics of the region are determined by the sequence and nature of manifestation of Mesozoic and Cenozoic orogenic processes at the boundaries of the Eurasian and Okhotsk Sea lithospheric paleoplates. The study of regional shear zones developing along the Okhotsk-Chukotka suture zone and the Okhotsk-West Kamchatka Block demonstrated their vital influence on the morphology of sedimentary basins. Thus, the tectonic activity in the Okhotsk-Chukotka shear zone extending subparallel to the Eurasian coast, led to formation of an extensive network of feather dislocations and basins of two types: large longitudinal shear depressions (sedimentary basins that form due to extersion along strike-slip faults) and shear-pull-apart basins oriented at an angle to the axis of the main shear. Mapping of horst uplifts makes it possible to confirm the position of oil and gas formations prioritized for exploration according to the structural criterion.