Review of the up-to-date state of the mineral resources base of uranium shows that the current value of uranium production from the Russian ore deposits can not supply even the country’s internal needs as at present so in the close five year future. In the vastest country, any large nor super-large uramum ore deposit was not discovered during last two decades or more. Actually advised for prospecting areas have within their limits an appraised amount of 5-10 thousand tons of the metal as hypothetical resources (Pi category), which indicates the principally low potential of those territories, the low probability to discover there some large uranium ore bodies. The situation needs to research some ways for more effective forecasting of promising uranium-bearing structures. For the purpose, the principal commercial type of uranium deposits are considered on the base of analysis of their ore-forming and uranium-concentrating processes. By example of the unique ore bodies of the Athabasca region, there are distinguished several, disengaged in time, preparative and concentrating processes subsequently participating in the uranium ore forming. Comparison of deposits in the Athabasca province and the Ladoga region shows that in the latter ones ore bodies are connected with the lesser number of oregenerating processes, and thus, those objects have the lower uranium-bearing potential. In the whole, analysis of the actual state of the uranium mineral resources base and the potential uranium-bearing of the Russia’s geological structures leads to conclusion about necessary strengthening of geological trend in metallogeny-forecasting and prospecting for uranium. It means development of the complex geological, geophysical, mineralogical-geochemical and some other typees of investigations aimed for revealing of the structural-substantial peculiarities in the uranium-promising formations and geological structures, as well as to thorough study of the ore-forming systems evolution.