Complex of geochemical studies in developing of Sibai chalcopyrite deposits are conducted. The peculiarities of the chemical composition of natural waters, the specificity of technogenic migration of ore elements in river sediments and soils, as well as the involvement of heavy metals into the biogeochemical cycle are established. The extent of transformation of natural geochemical processes in technogenesis is revealed. Approximate dimensions of man-made streams and scattering halos of ore metals are determined. The recommendations at reducing anthropogenic migration of elements are aimed.