The article explores the challenges facing Russia petrochemical industry over the past decade and examines the reasons behind its significant lag compared to other industrialized nations. It presents a review of academic research on clusters accompanied by a comparative analysis, generalization, and consolidation of factors influencing the development of the petrochemical industry in Russia. It is argued that advancing the petrochemical industry from production plants to integrated production complexes necessitates a shift towards clustering, which will improve resource utilization efficiency, bolster product competitiveness, and reduce production costs. The article examines and consolidates key cluster concepts, encompassing definitions, characteristics, composition, and constituent elements. It also examines strategic documents guiding the development of the petrochemical sector, assesses the progress made in forming petrochemical clusters in Russia, and draws upon European and Asian experiences and government support tools in the domain of petrochemical clusters. The successful development of petrochemical clusters in Russia is argued to be strongly dependent on state initiatives and support for infrastructure development. Additionally, the presence of research organizations within clusters is crucial for fostering high-tech product innovation and forming an efficient value chain that integrates research and development with specific assets. When establishing petrochemical clusters in Russia, it is essential to consider the unique characteristics of each cluster, including the types of raw materials and resources used, the necessary infrastructure, and the specific support measures and incentives provided by the state.