A rational series of technological solutions aimed at improving the efficiency of study and development of deposits and including seven stages is proposed: predictive assessment of ore contrast in the subsurface, assessment of the contrast of extracted ore of initial size, operational technological assessment of the obtained grades, ore preparation with the use of centrifugal-impact type apparatuses, maximum use of gravitational processes with full or partial abandonment of flotation schemes, enrichment of technological grades obtained by large lump processing The complex of innovative technologies for gold-sulfide, gold-quartz, copper-silver ores and copper ores with gold mineralization is given. The developed rational range of technological solutions is used in the creation of the concept of antimony industry development in the Republic of Sakha (Yakutia).