The Novomoskovsk region belongs to the industrially developed region, the geological environment of which, including surface and ground waters, is subjected to technogenic impact. Negative impact on surface and underground hydrosphere has an intensive exploitation of aquifers of coal deposits, water leveling activities at mining enterprises, construction of water reservoirs on rivers, water pollution by wastes of chemical industries. Signs of chloride and sulfate pollution of surface and ground water are recorded in the area of the mining allotment of the Novomoskovskiy Azot brine field and the adjacent territory. According to environmental studies the source of chloride pollution in the south of the territory are strong brines spilled on the ground surface during accidents at the brine field; sulfate pollution is associated with industrial effluents of hypo enterprises. Monitoring of natural waters in the area of the mining allotment of the Novomoskovsk brine field and the Lubovsky water intake shows that the aquatic environment is currently in quasi-static equilibrium in relation to anthropogenic loads.