The paper presents the results of constructing effective relay protection in the power supply system of a mining and processing plant (MPP). A brief description of the MPP is given, the power supply and substitution circuits used to calculate the short-circuit currents are given. A statistical analysis of failures in the electric network of the MPP has been carried out, which makes it possible to draw conclusions about the nature of failures ranges. Analysis of the registered faults shows that a significant part of them are line-to-earth faults, which in most cases turn into multiphase short circuits, which are interrupted by overcurrent protection. In order to improve the efficiency and reliability of the relay protection, the power supply scheme of the MPP was refined and analyzed. The calculation of the short-circuit currents was made, which made it possible to calculate the settings of the relay protection and give recommendations on the place of its installation and adjustment in order to ensure the normal operation of electricity consumers. To reduce the number of failures to the cable insert on the line leaving the administrative and household complex (AHC), and to increase the reliability of power supply to consumers, it is advisable to divide the capacities of the existing 10 kV line into two parallel ones by laying a second line. It is recommended to install a current cut-off on the line outgoing to the AHC, the feasibility of the installation of which was shown by calculations. This will reduce the chance of failures to the cable gland. Data on the setting currents of overcurrent protection and current cut-off are given on the selectivity card.